Akrofi-Christaller Institute has a vigorous publications programme, including theses, historical and theological studies and studies of important issues for social and cultural transformation. These are all geared towards enhancing the Institute's usefulness to the churches in their witness to the Kingdom of God in Ghanaian society and in Africa as a whole.

The Institute publishes its own internationally refereed journal, Journal of African Christian Thought.

The Institute is the editorial office for Regnum Africa publications. Books published include:

Kwame Bediako, Jesus in Africa - The Christian Gospel in African History and Experience (2000).

Kä Mana, Christians and Churches of Africa Envisioning the Future - Salvation in Christ and the Building of a New African Society (2002).

Mercy Amba Oduyoye, Beads and Srands - Reflections of an African Woman on Christianity in Africa (2002).

Laurenti Magesa, African Catholicism in Transition, Models of the Church for a New Century (2007)

These four are in a series called ‘Theological Reflections from the South’, which is designed to disseminate the fruit of creative thinking of African theologians, in the first instance, among ministers of churches, theological students and educated lay Christians.

ACI is also concerned to develop biblical and Christian literature in Ghanaian languages. In 2006 the Institute launched a new series: Nyamedua Series in African Mother-Tongue Theology. The first book in this series is a Christological study in Ga, the language of Accra, by ACI staff member, Rev Dr Philip Tete Laryea: Yesu, Homowo Nuntso (Jesus, Lord of Homowo).

Regnum Africa is also concerned to publish the fruits of research that records and documents the oral history and theology of churches in Ghana. Several theses of the Institute are in line for publication.

Regnum Africa has also published:

Ype Schaaf, On their Way Rejoicing: The History and Role of the Bible in Africa (rev. ed. 2003).